Endocrine Abstracts

Introduction: Selenium (Se) deficiency is a known risk factor for autoimmune thyroid diseases including Graves’ orbitopathy (GO).Objective: To determine the concentration of Se in serum and to determine the dependency of Se concentration on known markers of disease severity: the TRAB levels and the CAS (clinical activity score) in patients with GO.Material: 64 patients (50 women, 14 men; average age- 54.5 years) with active, m...

Introduction: Vitamin D deficiency (25OHD) is common in women with polycystic ovary syndrome (PCOS). 67–85% of female patients with PCOS have low concentration level of 25OHD (<20 ng/ml). It is believed that low concentration levels of 25OHD may exacerbate the symptoms of PCOS.Aim: The aim of the study was to evaluate the concentration of 25OHD in women diagnosed with PCOS and the analysis of the relationship between 25OHD concentration and such...

Introduction: In ATA recommendations (2016) a delayed risk stratification (DRS) system proposed by D.P. Momesso et al. was accepted as a diagnostic tool for the risk stratification of unfavorable clinical outcome and for monitoring the clinical outcome in differentiated thyroid cancer (DTC) patients treated without radioactive iodine (RAI).The aim of the study: To evaluate the DRS system in patients with low clinical stage (pT1aN0/Nx).<p class="abste...

Introduction: Radioiodine therapy is considered as a risk factor for the development of Graves’ orbitopathy (GO) de novo or worsening of pre-existing orbitopathy. This risk is estimated in the available literature as up to 15–20%. Steroid cover is considered to eliminated this risk.Objective: The aim of our study was to established the relationship between the occurrence of GO and treatment with radioiodine. And the analysis of the time of appe...

Background: A dynamic risk stratification with modified initial estimated risk based on response to therapy and disease course is one of the crucial changes adopted recently by the American Thyroid Association (ATA). The analysis of BRAF status is not routinely recommended by ATA, although this finding may be advantageous to individualized risk-adapted approach in papillary thyroid cancer (PTC). The methods used to detect the BRAF V600E are known of variation...

Introduction: Obesity is a serious health problem worldwide, especially in well developed countries. It is a cause of various diseases, including thyroid cancer. The relationship between obesity and prognostic factors of thyroid cancer is uncertain.Aim of the study: Evaluation of relationship between the body mass index (BMI) and clinicopathological features increasing the risk of poor clinical course, treatment response and clinical outcome in patients ...